Alternative pre-mRNA Splicing: Theory and Protocols
| Author | : | |
| Rating | : | 4.62 (686 Votes) |
| Asin | : | 3527326065 |
| Format Type | : | paperback |
| Number of Pages | : | 660 Pages |
| Publish Date | : | 2014-07-18 |
| Language | : | English |
DESCRIPTION:
A theoretical introduction and practical guide for molecular biologists, geneticists,clinicians and every researcher interested in alternative splicing. These 43 practical chapters cover: Basic methods, Detection of splicing events, Analysis of alternative pre-mRNA splicing in vitro and in vivo, Manipulation of splicing events, and Bioinformatic analysis of alternative splicing. This book was written for graduate and medical students, as well as clinicians and postdoctoral researchers. Website: wiley-vch/home/splicing. It describes the theory of alternative pre-mRNA splicing in twelve introductory chapters and then introduces protocols and their theoretical background relevant for experimental research
"Outstanding reviews by experts in alternative and constitutive splicing." according to Tragic City. Outstanding reviews by experts in alternative and constitutive splicing. Co-editor Stamm is a true scholar. It's a must read for anyone interested in the biochemistry and regulation of splicing.
"This book, prepared within the context of the EURASNET framework, is the first of its kind and, as such, an important piece of scientific literature, which will inspire more investigators to enter the rising field of alternative pre-mRNA splicing." (Biotechnology Journal, April 2012)
His PhD research in Biochemistry was carried out at the University of London, followed by postdoctoral research at Harvard Medical School. His research focuses on the structure and mechanism of the spliceosome. . His research focuses on mechanisms and regulation of alternative splicing, withthe aim to apply the fi ndings to the Prader-Willi Syndrome and Spinal Muscular Atrophy.Chris Smith is Professor